Motif ID: FOX{C1,C2}.p2

Z-value: 1.272


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
Foxc1 17300 forkhead box C1
Foxc2 14234 forkhead box C2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxc1chr13_+_318985010.064.5e-01Click!
Foxc2chr8_+_1236400690.018.9e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_45368443 39.911 Col3a1
collagen, type III, alpha 1
chr1_+_196765124 22.620 Cd34
CD34 antigen
chr3_+_137949734 21.122 Adh1
alcohol dehydrogenase 1 (class I)
chr11_+_28821585 20.983 Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr1_-_174228105 18.852 NM_178405
Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_+_45368382 18.803 NM_009930
Col3a1
collagen, type III, alpha 1
chr6_-_83486194 18.404 NM_009610
Actg2
actin, gamma 2, smooth muscle, enteric
chr1_-_170362298 17.423 Pbx1
pre B-cell leukemia transcription factor 1
chr1_+_196765014 17.397 NM_001111059
NM_133654
Cd34

CD34 antigen

chr6_-_55124983 16.858 NM_009349
Inmt
indolethylamine N-methyltransferase
chr1_+_137737433 16.331 NM_001130176
Tnnt2
troponin T2, cardiac
chr19_+_23241546 16.125 Klf9
Kruppel-like factor 9
chr9_-_71440061 15.686 NM_001033208
Gcom1
GRINL1A complex locus
chr4_-_61179982 15.095 Mup1
major urinary protein 1
chr11_-_55223449 14.691 Sparc
secreted acidic cysteine rich glycoprotein
chr4_-_60594496 14.269 Mup1
major urinary protein 1
chr12_-_105066203 14.242 Serpina1b
serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr4_-_60594469 14.103 Mup1
major urinary protein 1
chr1_-_45460310 14.084 Col5a2
collagen, type V, alpha 2
chr11_+_108256590 13.775 NM_013475
Apoh
apolipoprotein H

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
4.94 3.09e-03 GO:0051346 negative regulation of hydrolase activity
4.14 4.46e-02 GO:0043062 extracellular structure organization
2.83 3.86e-02 GO:0006461 protein complex assembly
2.82 4.13e-02 GO:0070271 protein complex biogenesis
2.72 4.35e-02 GO:0006753 nucleoside phosphate metabolic process
2.72 4.35e-02 GO:0009117 nucleotide metabolic process
2.55 2.41e-02 GO:0007155 cell adhesion
2.54 2.55e-02 GO:0046483 heterocycle metabolic process
2.53 2.77e-02 GO:0022610 biological adhesion
2.38 1.95e-02 GO:0055114 oxidation-reduction process
1.88 1.97e-02 GO:0044281 small molecule metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
3.53 7.43e-04 GO:0005792 microsome
3.44 1.06e-03 GO:0042598 vesicular fraction
3.17 1.61e-02 GO:0005578 proteinaceous extracellular matrix
2.98 2.00e-02 GO:0031012 extracellular matrix
2.54 5.46e-05 GO:0005624 membrane fraction
2.53 5.05e-07 GO:0000267 cell fraction
2.42 1.62e-04 GO:0005626 insoluble fraction
2.32 8.32e-03 GO:0005615 extracellular space
2.08 1.41e-02 GO:0044421 extracellular region part
1.86 1.48e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
10.72 2.47e-02 GO:0070330 aromatase activity
10.00 3.48e-02 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
9.06 6.91e-04 GO:0046332 SMAD binding
6.86 4.99e-05 GO:0004867 serine-type endopeptidase inhibitor activity
6.40 3.53e-05 GO:0046906 tetrapyrrole binding
5.74 9.68e-04 GO:0020037 heme binding
4.91 7.47e-04 GO:0004866 endopeptidase inhibitor activity
4.73 1.13e-03 GO:0061135 endopeptidase regulator activity
4.65 1.37e-03 GO:0030414 peptidase inhibitor activity
4.29 1.52e-03 GO:0061134 peptidase regulator activity
3.98 7.21e-03 GO:0005506 iron ion binding
3.88 5.97e-04 GO:0004857 enzyme inhibitor activity
2.63 1.07e-02 GO:0005509 calcium ion binding
1.38 2.24e-02 GO:0003824 catalytic activity
1.36 1.74e-02 GO:0005515 protein binding